Gene name:
SLC12A1 (NKCC2) ;
Protein name:
Solute carrier family 12 member 1 ;
Alternative:
Kidney-specific Na-K-Cl symporter ;Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MSLNNSSNVF | LDSVPSNTNR | FQVSVINENH | ESSAAADDNT | DPPHYEETSF |
100:
GDEAQKRLRI | SFRPGNQECY | DNFLQSGETA | KTDASFHAYD | SHTNTYYLQT |
150:
FGHNTMDAVP | KIEYYRNTGS | ISGPKVNRPS | LLEIHEQLAK | NVAVTPSSAD |
200:
RVANGDGIPG | DEQAENKEDD | QAGVVKFGWV | KGVLVRCMLN | IWGVMLFIRL |
250:
SWIVGEAGIG | LGVLIILLST | MVTSITGLST | SAIATNGFVR | GGGAYYLISR |
300:
SLGPEFGGSI | GLIFAFANAV | AVAMYVVGFA | ETVVDLLKES | DSMMVDPTND |
350:
IRIIGSITVV | ILLGISVAGM | EWEAKAQVIL | LVILLIAIAN | FFIGTVIPSN |
400:
NEKKSRGFFN | YQASIFAENF | GPRFTKGEGF | FSVFAIFFPA | ATGILAGANI |
450:
SGDLEDPQDA | IPRGTMLAIF | ITTVAYLGVA | ICVGACVVRD | ATGNMNDTII |
500:
SGMNCNGSAA | CGLGYDFSRC | RHEPCQYGLM | NNFQVMSMVS | GFGPLITAGI |
550:
FSATLSSALA | SLVSAPKVFQ | ALCKDNIYKA | LQFFAKGYGK | NNEPLRGYIL |
600:
TFLIAMAFIL | IAELNTIAPI | ISNFFLASYA | LINFSCFHAS | YAKSPGWRPA |
650:
YGIYNMWVSL | FGAVLCCAVM | FVINWWAAVI | TYVIEFFLYV | YVTCKKPDVN |
700:
WGSSTQALSY | VSALDNALEL | TTVEDHVKNF | RPQCIVLTGG | PMTRPALLDI |
750:
THAFTKNSGL | CICCEVFVGP | RKLCVKEMNS | GMAKKQAWLI | KNKIKAFYAA |
800:
VAADCFRDGV | RSLLQASGLG | RMKPNTLVIG | YKKNWRKAPL | TEIENYVGII |
850:
HDAFDFEIGV | VIVRISQGFD | ISQVLQVQEE | LERLEQERLA | LEATIKDNEC |
900:
EEESGGIRGL | FKKAGKLNIT | KTTPKKDGSI | NTSQSMHVGE | FNQKLVEAST |
950:
QFKKKQEKGT | IDVWWLFDDG | GLTLLIPYIL | TLRKKWKDCK | LRIYVGGKIN |
1000:
RIEEEKIVMA | SLLSKFRIKF | ADIHIIGDIN | IRPNKESWKV | FEEMIEPYRL |
1050:
HESCKDLTTA | EKLKRETPWK | ITDAELEAVK | EKSYRQVRLN | ELLQEHSRAA |
1099:
NLIVLSLPVA | RKGSISDLLY | MAWLEILTKN | LPPVLLVRGN | HKNVLTFYS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Rabbit
Mouse
ELISA Kit for Human Solute carrier family 12 member 1
ELISA Kit for Human Solute carrier family 12 member 1
ELISA Kit for Human Solute carrier family 12 member 1
ELISA Kit for Human Solute carrier family 12 member 1
CLIA Kit for Human Solute carrier family 12 member 1
CLIA Kit for Human Solute carrier family 12 member 1
CLIA Kit for Human Solute carrier family 12 member 1
CLIA Kit for Human Solute carrier family 12 member 1
Polyclonal Antibody for Human Solute carrier family 12 member 1
Polyclonal Antibody for Human Solute carrier family 12 member 1
Polyclonal Antibody for Human Solute carrier family 12 member 1
Polyclonal Antibody for Human Solute carrier family 12 member 1
Monoclonal Antibody for Human Solute carrier family 12 member 1
Monoclonal Antibody for Human Solute carrier family 12 member 1
Monoclonal Antibody for Human Solute carrier family 12 member 1
Monoclonal Antibody for Human Solute carrier family 12 member 1
Protein for Human Solute carrier family 12 member 1
Protein for Human Solute carrier family 12 member 1
Protein for Human Solute carrier family 12 member 1
Protein for Human Solute carrier family 12 member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM F);VARIANTS BS1 PHE-272 AND ASN-648;VARIANT ALA-958;ALTERNATIVE SPLICING
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);VARIANT ALA-958
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ENZYME REGULATION